MIA experts collaborate on groundbreaking research
16 January 2019
In another collaborative effort in our quest to reach zero deaths from melanoma, Melanoma Institute Australia (MIA) has contributed its expertise to an exciting new study published in the prestigious journal Nature.
Led by researchers from Perth’s Telethon Kids Institute and The University of Melbourne, the study aimed to discover the specific mechanisms behind immune-mediated equilibrium – the reason malignant cells can remain dormant in a patient for years without manifesting as disease.
MIA’s Co-Medical Director, Professor Richard Scolyer, post-doctoral researcher, Dr James Wilmott, and collaborator, Dr Mainthan Palendira, were all responsible for intellectual input and data interpretation. MIA PhD student Jarem Edwards assisted in performing experiments for the study and analysing the resultant data.
The study found that a particular type of immune cell - tissue-resident memory (TRM) T cells - were responsible for patrolling melanoma cells and keeping them in check. When they removed this type of cell from the body of mice with melanoma, the melanoma cells were re-established and allowed to grow.
The hope is that this research will pave the way for investigators to manipulate this mechanism and control and maintain melanoma, and other cancers, in a dormant state for life, effectively curing patients.
Image: Imaging of cells keeping cancer in dormancy - Jason Waithman research.png (Telethon Kids Institute)
We want to thank every member of Team Melanoma and everyone who donated to them. With your help, we are moving closer to our goal of zero deaths from melanoma!
Lauren O'Brien tells us why she's running for a cause close to her heart
MIA could not do what we do without the incredible support and effort of our community fundraisers. We’d like to highlight some of the wonderful events organised by our community in
An international study, led by researchers from Melanoma Institute Australia, QIMR Berghofer Medical Research Institute and The University of Sydney as part of the Australian Melanoma Genome Project, has discovered that a drug traditionally used to treat a
Researchers from Melanoma Institute Australia took centre stage at the American Society of Clinical Oncology Annual Meeting in Chicago. Results presented by MIA’s contingent have the potential to create better patient outcomes and change the way advanced melanoma
Today is International Clinical Trials Day – a day to recognise and thank the amazing people who conduct, organise, and coordinate clinical trials.
“I’m the age Emma was when she passed away. It almost feels
As always, part of the PBAC process invites clinicians, patients and other stakeholders in the cancer community to make submissions
As always, part of the PBAC process invites clinicians, patients and other stakeholders in the cancer community to make submissions in support of the PBS listing.
MIA had four winners in the 2017 Premiers Awards. Find out how winning has influenced their work over the past year.
Cancer Council awards Melanoma Institute Australia researchers funding for ground-breaking cancer research projects
Almost $9 million of new funding was awarded to 13 ground-breaking cancer research projects at the 2019 Cancer Council NSW Research Awards.
Georgina V. Long is co-medical director of Melanoma Institute Australia and Chair of Melanoma Medical Oncology and Translational Research. She is the first woman president of the Society for Melanoma Research.
Quintessential Aussie girl and media personality Sophie Monk has been announced as a National Ambassador for Melanoma Institute Australia (MIA) and its national awareness and fundraising campaign, Melanoma March.
Australian researchers have for the first time identified specific cells and receptors in the immune system which predict how a patient will respond to treatment with immunotherapies, potentially paving the way for the development of personalised therapy for all cancer patients.
Melanoma March is thrilled to introduce Ricky as our official Principal Partner for 2019!
World record holder, Olympian and Australian swimming champion Cate Campbell has been announced as National Ambassador for Melanoma Institute Australia (MIA) and its national awareness and fundraising campaign, Melanoma March.
MIA's expertise was essential to a recent Nature publication spearheaded by Perth’s Telethon Kids Institute and The University of Melbourne.
MIA is delighted to be hosting the MD Anderson pathologist on his first ever trip to Australia.
Clinicians, patients and other stakeholders in the cancer community are invited to make submissions in support of the PBS listing for dabrafenib and trametinib.
Three students from Arden Anglican School in Epping have won Melanoma Institute Australia’s (MIA) inaugural SunSafe Student Ambassador Award.