MIA experts collaborate on groundbreaking research
16 January 2019
In another collaborative effort in our quest to reach zero deaths from melanoma, Melanoma Institute Australia (MIA) has contributed its expertise to an exciting new study published in the prestigious journal Nature.
Led by researchers from Perth’s Telethon Kids Institute and The University of Melbourne, the study aimed to discover the specific mechanisms behind immune-mediated equilibrium – the reason malignant cells can remain dormant in a patient for years without manifesting as disease.
MIA’s Co-Medical Director, Professor Richard Scolyer, post-doctoral researcher, Dr James Wilmott, and collaborator, Dr Mainthan Palendira, were all responsible for intellectual input and data interpretation. MIA PhD student Jarem Edwards assisted in performing experiments for the study and analysing the resultant data.
The study found that a particular type of immune cell - tissue-resident memory (TRM) T cells - were responsible for patrolling melanoma cells and keeping them in check. When they removed this type of cell from the body of mice with melanoma, the melanoma cells were re-established and allowed to grow.
The hope is that this research will pave the way for investigators to manipulate this mechanism and control and maintain melanoma, and other cancers, in a dormant state for life, effectively curing patients.
Image: Imaging of cells keeping cancer in dormancy - Jason Waithman research.png (Telethon Kids Institute)
MIA has presented promising data regarding progression-free survival rates for advanced melanoma patients at the ESMO 2019 Congress in Barcelona.
Another month has flown by and yet again we have a host of amazing community fundraisers who generously gave up their time to help us reach our goal of zero deaths from melanoma.
Comments in favour of giving patients with BRAF-positive melanoma access to first-line immunotherapy need to be submitted online prior to October 9, 2019.
Jay's Longest Melanoma March documentary is screening this Sunday 22 September at 1pm (AEST) on Channel 10, capturing behind the scenes of the 2000km walk, Adelaide to Sydney in 50 days. Uniting to end melanoma.
It’s been a month since we highlighted some of our incredibly generous community fundraisers. We thought we’d have a look back at August and put the spotlight on more of the wonderful people who give up their time to fundraise for MIA, so we can continue to edge closer to our goal of zero deaths from melanoma.
They are a formidable team - in work and in play
This week, Melanoma Institute Australia hosted the first of six
Federal government urged
We want to thank every member of Team Melanoma and everyone who donated to them. With your help, we are moving closer to our goal of zero deaths from melanoma!
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As always, part of the PBAC process invites clinicians, patients and other stakeholders in the cancer community to make submissions
As always, part of the PBAC process invites clinicians, patients and other stakeholders in the cancer community to make submissions in support of the PBS listing.