MIA in the spotlight at ASCO virtual conference
30 May 2020
This year’s American Society of Clinical Oncology (ASCO) Annual Meeting has gone virtual, with researchers from MIA once again in the spotlight. Usually attended by over 40,000 professionals, ASCO’s Annual Meeting showcased global advances in research and treatment, all of which impact patient outcomes.
Headlining MIA’s contribution at ASCO 20 Virtual was Dr Ines Silva, a clinical fellow and post-doctoral researcher at MIA, who was awarded the prestigious Bradley Stuart Beller Endowed award for best abstract.
Dr Silva’s abstract related to an oral presentation delivered virtually at ASCO, assessing the impact of Ipilimumab-based immunotherapy in patients with metastatic melanoma whose disease had already proven resistant to anti-PD1 monotherapy.
The multicentre retrospective study involved 355 patients with Stage III or Stage IV melanoma whose cancer had progressed or recurred despite having anti-PD1 monotherapy. 46% of these patients were then treated with ipilimumab alone, with 54% receiving combination ipilimumab and anti-PD1 therapy.
In patients who received the follow up combination therapy, there was a higher response rate (32%) as well as longer progression free survival (25% at 12 months) and overall survival (58% at 12 months) compared to IPI alone. Importantly, IPI+anti-PD1 was not associated with more severe side effects than IPI monotherapy.
Dr Silva and the MIA team created clinical predictive models to help identify the patients who will benefit from these treatments.
‘It was an honour to deliver the oral presentation virtually at ASCO 20 Virtual,’ said Dr Silva. ‘Although we weren’t together physically, still being able to share insights and learnings globally was vitally important in ensuring we continue on our path to saving more lives from melanoma.’
Also awarded at ASCO 20 Virtual were Dr Adriana Hepner and Dr Lauren Brown who received merit awards for abstracts submitted. Overall, MIA researchers and clinicians contributed to 21 abstracts featured at ASCO.
‘We are extremely proud of our ongoing contribution to the global effort to save lives from melanoma, with Dr Silva’s prestigious award proof that we continue to lead the way in changing the treatment landscape for melanoma patients,’ MIA Co-Medical Director Professor Georgina Long said.
‘Our mission is zero deaths from melanoma, and by collaborating with our colleagues on the world stage we are confident we are on track to reach that goal within our lifetime,’ added MIA Co-Medical Director Professor Richard Scolyer.
Register to view Dr Silva's video and slides here: Dr Silva presentation
See the ASCO 20 Virtual Program here: ASCO 20 Virtual
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“I had a complete response within about six months. All of my tumours disappeared."
‘We are extremely proud of our ongoing contribution to the global effort to save lives from melanoma, with Dr Silva’s prestigious award proof that we continue to lead the way,'
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